Publications

CaTSiT was used in the following publications:

Anja Bethge, Udo Schumacher, Andreas Wree and Gero Wedemann: Are Metastases from Metastases Clinically Relevant? Computer Modelling of Cancer Spread in a Case of Hepatocellular Carcinoma, PLoS ONE 7(4), 2012.
DOI: 10.1371/journal.pone.0035689
Gero Wedemann, Anja Bethge, Volker Haustein and Udo Schumacher: Computer Simulation of the Metastatic Cascade, In Metastasis Research Protocols, 2nd Edition. Methods in Molecular Biology 1070, p. 107-116. Springer, New York, 2014.
Tobias Brodbeck, Nina Nehmann, Anja Bethge, Gero Wedemann and Udo Schumacher: Perforin-dependent direct cytotoxicity in Natural killer cells induces considerable knockdown of spontaneous lung metastases and computer modelling-proven tumor cell dormancy in a HT29 human colon cancer xenograft mouse model, Molecular Cancer 13(1), 2014.
DOI: 10.1186/1476-4598-13-244
Anja Bethge, Udo Schumacher and Gero Wedemann: Simulation of Metastatic Progression using a Computer Model including Chemotherapy and Radiation Therapy, Journal of Biomedical Informatics, 57, p. 74–87, 2015.
Thorsten Frenzel, Bertin Hoffmann, Rüdiger Schmitz, Anja Bethge, Udo Schumacher and Gero Wedemann : Radiotherapy and chemotherapy change vessel tree geometry and metastatic spread in a small cell lung cancer xenograft mouse tumor model, PLoS ONE 12(11), e0187144, 2017.